点评详情
发布于:2019-7-22 03:33:23  访问:16 次 回复:0 篇
版主管理 | 推荐 | 删除 | 删除并扣分
Ry density (FCD) and mean velocity with Microscan and MAS (MicroVision
Exclusion criteria: hepatopathy at admission, age <18 years and >60 years, BMI > 30, clinical factors favouring buy CS-3290 splanchnic hypoperfusion. Hepatic cytonecrosis indexes, GGT, serum amylases are well correlated to splanchnic perfusion indexes (serum lactates, FCD and regional PCO2) so their increase apparently is not due to splanchnic hypoperfusion. Patient 1 (propofol, fentatienil early replaced with sodium thiopental, midazolam), increase of PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28239662 transaminases when PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/27443522 midazolam was stopped. Because of the beginning of an epileptic status, the patient was eliminated from the study. Patient 2 (propofol, midazolam, fentatienil), increase of transaminases associated with the paradoxical increase of splanchnic perfusion. Patient 3 (propofol, midazolam, fentatienil), increase of transaminases and serum amylases is not associated with the splanchnic hypoperfusion. Serum amylases increase according to the increase of propofol dosage. Patient 4 (propofol, fentatienil), late increase of transaminases, serum amylases and GGT is associated with the propofol dosage. Conclusions Drugs used for the analgosedation seem responsible for the increase of transaminases but not for the decrease of splanchnic perfusion. This study has to be confirmed by other studies recruiting more patients and with more precise exclusion criteria. Reference 1. Jacobi J, et al.: Crit Care Med 2002, 30:119-141.P270 Short-term sevoflurane sedation using the anaesthetic conserving device AnaConDa?after cardiac surgery: feasibility, recovery and clinical issuesKD R m, MW Wolf, J Boldt, T Sch lhorn, A Schellhaass, SN Piper Klinikum Ludwigshafen, Germany Critical Care 2008, 12(Suppl 2):P270 (doi: 10.1186/cc6491) Introduction With the approval of the anaesthetic conserving device (AnaConDa?, inhalative sedation in the ICU has become feasible [1]. Isoflurane has been investigated in postoperative andLength of hospital stay (average, days) 18.66 15.16 1.2940 <0.Died (n) 4 3 Not significantExclusion (n) 1SAvailable online http://ccforum.com/supplements/12/Scritically ill patients using AnaConDa?[2,3], whereas sevoflurane sedation has only been reported in small observations [4,5]. This randomised, single-blinded, BIS-controlled study was to evaluate f.Ry density (FCD) and mean velocity with Microscan and MAS (MicroVision Medical, Amsterdam, The Netherlands), plasma disappearance ratio (PDR)Table 1 (abstract P268) Results Patients (n) Sedatonarcosis group (n = 21) Awake sedation group (n = 23) t0.05 P value MV (average, days) 6.37 4.38 1.8357 <0.05 Length of ICU stay (average, days) 9.06 7.22 1.28725 <0.with Pulsion LIMON (SEDA; Milano), intramucosal pH and regional PCO2 with Tonocap (GE Health Care), electrocardiography, mean arterial pressure and hematochemical examinations (transaminases, -glutamyl transpeptidase (GGT), serum bilirubin, serum amylases, serum lactates and drugs dosages). Exclusion criteria: hepatopathy at admission, age <18 years and >60 years, BMI > 30, clinical factors favouring splanchnic hypoperfusion. All the parameters are analysed at t0 (admission to the ICU) and then every 48 hours during the sedation (t1, t2, t3) and at its end (t4, t5) through the Friedman test (P < 0.05) and the Spearman test (P < 0.05 and R > 0.6). Results Increase of transaminases at the end of sedation in three of the four patients. Earlier increase of GGT in all patients. Serum bilirubin always in range. Increase of serum amylases in three of the four patients is correlated to propofol dosage. PDR always >16 /ml (cutoff of hepatic hypoperfusion). BSR always >0 during t1, t2, t3.
共0篇回复 每页10篇 页次:1/1
共0篇回复 每页10篇 页次:1/1
我要回复
回复内容
验 证 码
看不清?更换一张
匿名发表 
当前位置
脚注信息
版权所有 Copyright(C)2009-2017 北京众康中医养生堂专业调理